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--> Frontier Research Institute for Interdisciplinary SciencesTohoku University Directions 日本語 English CONTACT 日本語 English About FRISGreetingsOverviewMissionsOrganizationTenure track system in FRISMaps & DirectionsPublicationAnnual MeetingAbstract for Annual MeetingConsultation DeskResearcherAdvanced Interdisciplinary Research DivisionHiroshi MasumotoTakehito ShimatsuTakashi ItohKenji TomaShinsuke NiwaTakaaki TomaiCreative Interdisciplinary Research DivisionYuanyuan GuoMasaki OkumuraNguyen Tuan HungHiroshi UenoToshiharu IchinoseYuta KudoHiroya AbeYuta NakayasuNaoya KitajimaDaniel Pastor-GalanYasunori OkamotoTakuro IshiiMasaki YamadaYuta YamaneKexin XiongKohei ShimokawaShinichi SatoKotaro YasuiSUN SaiYuji SaitoAtsushi TaharaKyoko ChibaYuka HatanoHakuto SuzukiKaoru HiramotoHideaki T. MatsubayashiAseel Mahmoud Suleiman MarahlehSakura KiuchiShigeo S. 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The rupture of cerebral aneurysms results in subarachnoid hemorrhage, well known for its high mortality (more than 10,000 deaths each year in Japan). Thus, it has been of medical importance to investigate how cerebral aneurysms initiate and rupture. Although the mechanisms are still unclear, previous studies have suggested that ‘local mechanical forces/stimuli induced by blood flow’ could play an important role in the initiation of cerebral aneurysms. Our study focuses on the possible association between temporal/spatial fluctuations of the local mechanical forces/stimuli induced by blood flow and the initiation of cerebral aneurysms. The combined technique of medical image processing and computational fluid dynamics enables us to evaluate numerically such fluctuation phenomena in detail. The former is used to mimic subject-specific vascular geometries based on their CT/MRI images; the later is a technique that can be applied for simulating the blood flow numerically based on the equations of fluid dynamics. The combination of these techniques provides a framework for us to reproduce a ‘subject-specific blood flow dynamics’. We are conducting an interdisciplinary collaborative research intended to identify hemodynamic risk factors for cerebral aneurysms on the basis of the combined technique and a strong association with a medical researcher/institution. Figure: An example of 3D pulsatile flow computation Related Posts PAGE TOP Frontier Research Institute for Interdisciplinary Sciences About FRIS GreetingsOverviewMissionsOrganizationTenure track system in FRISMaps & DirectionsPublicationAnnual MeetingConsultation Desk Researcher Advanced Interdisciplinary Research DivisionCreative Interdisciplinary Research DivisionManaging & Planning DivisionEndowed Research DivisionsSenior-advisorVisiting Professors / Collaborative ResearchersSpecially-appointedOne-time members Feature TopicsFRIS InterviewsFRIS Hub Meeting Research Programs Open Research ProposalResearch Projects Recruit Open Staff PositionsHandbook for International Researchers FRIS CoRE FRIS CoRE FRIS Fund FRIS Fund for Early-Career Independent Researchers External Links for Early Career Researcher Support Division for Interdisciplinary Advanced Research and Education (DIARE) Ensemble Project for Early Career Researchers Support Program for the Article Processing Charge webmail LINK Copyrights © Frontier Research Institute for Interdisciplinary Sciences, Tohoku University All rights reserved. no cache